EPITHELIAL-CELL INVASION AND SURVIVAL OF BORDETELLA-BRONCHISEPTICA

被引：45

作者：

SCHIPPER, H

KROHNE, GF

GROSS, R

机构：

[1] UNIV WURZBURG,THEODOR BOVERI INST BIOWISSENSCH,BIOZENTRUM,LEHRSTUHL MIKROBIOL,D-97074 WURZBURG,GERMANY

[2] UNIV WURZBURG,THEODOR BOVERI INST BIOWISSENSCH,BIOZENTRUM,ELEKTRONENMIKROSKOPIE ABT,D-97074 WURZBURG,GERMANY

来源：

INFECTION AND IMMUNITY | 1994年 / 62卷 / 07期

关键词：

D O I：

10.1128/IAI.62.7.3008-3011.1994

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Wild-type Bordetella bronchiseptica and a bvg mutant strain were used for invasion and survival experiments in human Caco-2 and A549 epithelial cells. Both bacterial strains were able to enter and persist within the host cells for at least a week. A significant proportion of the bacteria from both B. bronchiseptica strains but not from Bordetella pertussis were found free in the cytoplasm, suggesting different invasion and survival strategies of the two species in epithelial cells.

引用

页码：3008 / 3011

页数：4

共 20 条

[1] A PHASE VARIANT OF BORDETELLA-PERTUSSIS WITH A MUTATION IN A NEW LOCUS INVOLVED IN THE REGULATION OF PERTUSSIS TOXIN AND ADENYLATE-CYCLASE TOXIN EXPRESSION [J].