SYNTHESES OF ISODITYROSINE, DITYROSINE AND RELATED-COMPOUNDS BY PHENOLIC OXIDATION OF TYROSINE AND PHENYLGLYCINE DERIVATIVES USING AN ELECTROCHEMICAL METHOD

被引:41
作者
NISHIYAMA, S
KIM, MH
YAMAMURA, S
机构
[1] Department of Chemistry, Faculty of Science and Technology, Keio University, Hiyoshi, Yokohama
关键词
D O I
10.1016/S0040-4039(00)74416-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The phenolic oxidation of L-tyrosine derivatives by electrolysis and zinc reduction produced the coupling products leading to isodityrosine and dityrosine. The oxidation mode could be controlled by altering halogen substituents (Br or I) at two ortho positions of phenol groups. Additionally, this methodology was applied to 4-hydroxy-D-phenylglycine derivatives, providing the corresponding oxidative products.
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页码:8397 / 8400
页数:4
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