RELATIONSHIP OF LETHAL MIDLINE GRANULOMA TO WEGENERS GRANULOMATOSIS

被引：21

作者：

BYRD, LJ

SHEARN, MA

TU, WH

机构：

[1] Department of Medicine, Kaiser Foundation Hospital, Oakland, California

[2] Kaiser Foundation Hospital, Oakland

[3] Permanente Medical Group, Kaiser Foundation Hospital, Oakland, California

[4] The Mayo Foundation, Rochester, Minnesota

[5] Associate Clinical Medicine, University of California Medical Center, San Francisco, California

来源：

ARTHRITIS AND RHEUMATISM | 1969年 / 12卷 / 03期

关键词：

D O I：

10.1002/art.1780120313

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Lethal midline granuloma (LMC) may remain localized or eventuate in systemic granulomatosis. In a search for predictive features, 10 patients with localized LMC were observed up to 9 years. Granuloma remained local in 5 and became systemic in 5. Friedmann's histologic criteria for distinction were not predictive. Polyarthralgia, cutaneous vasculitis, proteinuria, azotemia, leukocytosis, and rheumatoid factor developed in the patients in whom systemic granulomatosis ensued. Such findings in localized LMC suggest possible future Wegener's granulomatosis. Copyright © 1969 American College of Rheumatology

引用

页码：247 / &

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