LEUKOCYTE ADHERENCE INHIBITION AND IMMUNOREACTIVITY IN PROSTATIC CANCER .2. TISSUE-SPECIFICITY AND DISEASE-SPECIFICITY OF ANTI-TUMOUR CELL-MEDIATED-IMMUNITY

Tissue- and disease-specificities of the reactivity of peripheral blood leukocytes from 20 prostatic cancer patients to malignant prostatic tissue were evaluated. Results of leukocyte adherence inhibition, employed previously, suggested antitumor cell-mediated immunity. Absence of significant reactivity in prostatic cancer patients to tissues other than malignant prostate and in non-prostatic cancer patients (including patients with benign disease of the prostate) to malignant prostate confirms earlier observations. The identification of prostatic tumor-associated antigens and of tumor-associated immunity in prostatic carcinoma is suggested.