IFOSFAMIDE IN PLASMA-CELL LEUKEMIA - A REPORT OF 2 CASES AND REVIEW OF THE LITERATURE

被引：12

作者：

MALHOTRA, H ^{[1
]}

DHABHAR, BN ^{[1
]}

SAIKIA, TK ^{[1
]}

GOPAL, R ^{[1
]}

NADKARNI, KS ^{[1
]}

NAIR, CN ^{[1
]}

ADVANI, SH ^{[1
]}

机构：

[1] TATA MEM HOSP,DEPT MED ONCOL,BOMBAY 400012,INDIA

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 1992年 / 40卷 / 03期

关键词：

MYELOMA; IFOSFAMIDE; RESPONSE;

D O I：

10.1002/ajh.2830400313

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report two patients with primary plasma cell leukemia (PCL) treated with a single agent, ifosfamide. One patient had a total disappearance of plasma cells (PC) from the peripheral blood and the bone marrow and disappearance of the myeloma protein, is disease free 8 months after completion of treatment, and alive 14 months after diagnosis. The second patient had a partial response with persistence of plasma cells in the bone marrow lasting 7 months, after which she had a frank relapse of the disease. We suggest that ifosfamide may be an active agent in plasma cell malignancies and needs further evaluation in multiple myeloma.

引用

页码：226 / 228

页数：3

共 21 条

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