DISTRIBUTION OF MESENTERIC AND SPLENIC BLOOD-FLOW IN CIRRHOSIS OF THE LIVER AS ESTIMATED BY RADIONUCLIDE ANGIOGRAPHY

被引：9

作者：

HAMATO, N ^{[1
]}

MORIYASU, F ^{[1
]}

SOMEDA, H ^{[1
]}

NABESHIMA, M ^{[1
]}

FUJIMOTO, M ^{[1
]}

NISHIKAWA, K ^{[1
]}

OKUMA, M ^{[1
]}

机构：

[1] KYOTO UNIV,FAC MED,DEPT INTERNAL MED 1,54 SHOGOIN KAWAHARA CHO,SAKYO KU,KYOTO 606,JAPAN

来源：

INTERNAL MEDICINE | 1993年 / 32卷 / 06期

关键词：

SPLANCHNIC BLOOD FLOW; HEMODYNAMICS;

D O I：

10.2169/internalmedicine.32.445

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We used radionuclide angiography following an injection of 185 MBq Tc-99m tin colloid as a non-invasive method for measuring the mesenteric and portal components of the total hepatic circulation, according to the method of Fleming et al (J Nucl Med 24; 1983). Fifty-seven patients with cirrhosis and 33 controls were examined. The relative mesenteric flow (MF) and the relative portal flow (PF) were 68.6+/-8.5% and 78.6+/-5.9%, respectively, in the control group. These values were 42.0+/-16.4% and 70.9+/-8.9%, respectively in the cirrhosis group, and were significantly lower than in the controls. In the cirrhosis group, the reduction in PF was small, while that in MF was large. Consequently, we found that portal blood flow was relatively well maintained in the cirrhosis patients, while the contribution of splanchnic blood flow to the portal flow was relatively reduced.

引用

页码：445 / 448

页数：4

共 13 条

[1]

Schenk W.G., McDonald J.C., McDonald K., Drapanas T., Direct measurement of hepatic blood flow in surgical patients with related observations on hepatic flow dynamics in experimental animals, Ann Surg, 156, (1962)

[2]

Tygstrup N., Winkler K., Mellemgaard K., Andreassen M., Determination of the hepatic arterial blood flow and oxygen supply in man by clamping the hepatic artery during surgery, J Clin Invest, 41, (1962)

[3]

Fleming J.S., Ackery D.M., Walmsley B.H., Karran J., Scintigraphic estimation of arterial and portal blood supplies to the liver, J Nucl Med, 24, (1983)

[4]

Sarper R., Tarcan Y.A., An improved method of estimating portal venous fraction of total hepatic blood flow from computerized radionuclide angiography, Radiology, 147, (1983)

[5]

Biersack H.J., Torres J., Thelen M., Monzon O., Winkeler C., Determination of liver and spleen perfusion by quantitative sequential scintigraphy: Results in normal subjects and in patients with portal hypertension, Clin Nucl Med, 6, (1981)

[6]

Conn H.O., Apeek atthe Child-Turcotte classification, Hepatology, 1, (1981)

[7]

Leng B., O'Driscoll F.A., Majeed J.S., Critchley M., Hepatic perfusion index in cirrhotic livers - investigation of imaging and analytical procedures, Nucl Med Commun, 8, (1987)

[8]

Fleming J.S., A technique for the absolute measurement of activity using a gamma camera and computer, Phys Med Biol, 24, (1979)

[9]

Nishida O., Moriyasu F., Nakamura T., Et al., Interrelationship between splenic and superior mesenteric venous circulation manifested by transient splenic arterial occlusion using a balloon catheter, Hepatology, 7, (1987)

[10]

Nishida O., Moriyasu F., Nakamura T., Et al., Relationship between splenic and superior mesenteric venous circulation, Gastroenterology, 98, (1990)

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