KINETICS OF CURING AND PHYSICOMECHANICAL BEHAVIOR OF SILICONE MEMBRANE

被引：15

作者：

BOGNER, RH ^{[1
]}

LIU, JC ^{[1
]}

CHIEN, YW ^{[1
]}

机构：

[1] RUTGERS STATE UNIV,COLL PHARM,CONTROLLED DRUG DELIVERY RES CTR,POB 789,BUSCH CAMPUS,PISCATAWAY,NJ 08855

来源：

JOURNAL OF CONTROLLED RELEASE | 1990年 / 14卷 / 01期

关键词：

controlled release membrane; crosslinking; curing kinetics; silicone membrane;

D O I：

10.1016/0168-3659(90)90056-Y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The curing kinetics and cure dependence of properties of a silicone membrane were evaluated. The curing process has been shown to be quite temperature sensitive, suggesting that a longer processing time is required to cure the device at a more moderate temperature. However, curing temperature results at room in a substantially looser polymer network in the membrane. In order to investigate the cure dependence of membrane properties, stable partially cured membranes were prepared. The elasticity of partially cured membranes was observed to drop dramatically. However, the membrane permeability to testosterone for even the most poorly cured membranes was noted to be within the normal variation in permeability of fully cured membranes. © 1990.

引用

页码：11 / 19

页数：9

共 16 条

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