HUMAN CHORIONIC-GONADOTROPIN AND TRISOMY-18

被引：4

作者：

BARKAI, G ^{[1
]}

CHAKI, R ^{[1
]}

SOCHAT, M ^{[1
]}

GOLDMAN, B ^{[1
]}

机构：

[1] BEILINSON MED CTR,IL-49100 PETAH TIQWA,ISRAEL

来源：

AMERICAN JOURNAL OF MEDICAL GENETICS | 1991年 / 41卷 / 01期

关键词：

TRISOMY-18; MATERNAL SERUM; LOW BETA-HCG;

D O I：

10.1002/ajmg.1320410115

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Estimation of maternal serum-beta-hCG is used in conjunction with alpha-fetoprotein (AFP) and estriol (E3) for estimating the risk of Down syndrome (DS) affected fetuses. However, low hCG levels have not been regarded as having clinical significance. We report on 2 patients with trisomy 18 fetuses in whom antenatal screening showed extremely low hCG levels (0.05 and 0.15 MOM). Low hCG levels might indicate increased risk for trisomy 18 despite low estimated risk for DS.

引用

页码：52 / 53

页数：2