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SISTER CHROMATID EXCHANGES AND CHROMOSOME-ABERRATIONS IN LYMPHOCYTES OF NURSES HANDLING ANTINEOPLASTIC DRUGS

被引：35
作者：
GOLONIBERTOLLO, EM
TAJARA, EH
MANZATO, AJ
VARELLAGARCIA, M
机构：
[1] UNIV NACL ESTADUAL SAO PAULO,IBILCE,DEPT BIOL,CX POSTAL 136,BR-15055 SAO JOSE PRETO,SP,BRAZIL
[2] UNIV NACL ESTADUAL SAO PAULO,IBILCE,DEPT CIENCIAS COMPUTACAO & ESTAT,SAO JOSE RIO PRE,SP,BRAZIL
[3] FAC MED SAO JOSE RIO PRETO,DEPT CIENCIAS BASICAS,SAO JOSE RIO PRE,SP,BRAZIL
来源：
INTERNATIONAL JOURNAL OF CANCER | 1992年 / 50卷 / 03期
关键词：
D O I：
10.1002/ijc.2910500302
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Chromosomal aberrations (CA) and sister-chromatid exchanges (SCE) were investigated in peripheral lymphocytes of 15 nurses and nurse's aides handling cytostatic agents in hospital oncology units. Significantly increased frequencies were noted for both CA and SCE rates when the exposed individuals were compared with 15 nurses working in other hospital units and to a control sample matched by sex and age. This points to the need for emphasizing protective measures in the handling of anti-neoplastic agents.
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页码：341 / 344
页数：4
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