VIGABATRIN IN THE TREATMENT OF INFANTILE SPASMS

被引：53

作者：

VLES, JSH

VANDERHEYDEN, AMHG

GHIJS, A

TROOST, J

机构：

[1] UNIV LIMBURG HOSP,DEPT NEUROL,MAASTRICHT,NETHERLANDS

[2] UNIV LIMBURG HOSP,DEPT NEUROPSYCHOL,MAASTRICHT,NETHERLANDS

[3] UNIV LIMBURG HOSP,DEPT CHILD NEUROL,MAASTRICHT,NETHERLANDS

来源：

NEUROPEDIATRICS | 1993年 / 24卷 / 04期

关键词：

INFANTILE SPASMS; VIGABATRIN;

D O I：

10.1055/s-2008-1071546

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The anti-epileptic effect of vigabatrin as a first choice therapy was investigated in 6 children suffering from infantile spasms (IS). All 6 children showed a reduction in seizure frequency. Three children became seizure-free within a period of 2 weeks. Because our results suggest ''an all or nothing phenomenon'', a period of 2 weeks may be sufficient to evaluate the efficacy of vigabatrin in untreated infants suffering from IS. We suggest to use vigabatrin as a first choice anti-epileptic drug in infants with IS.

引用

页码：230 / 231

页数：2

共 13 条

[1]

Aicardi J, 1986, INT REV CHILD NEUROL, P17

[2]

Bayley, 1969, SCALES INFANT DEV

[3]

CHIRON L, 1990, LANCET, V10, P363

[4]

DULAC O, 1991, CHILD NEUROL, V6, P2530