INVIVO PROTON MAGNETIC-RESONANCE SPECTROSCOPY STUDIES OF HUMAN BRAIN

被引：81

作者：

NARAYANA, PA

JOHNSTON, D

FLAMIG, DP

机构：

[1] Department of Radiology, University of Texas Medical School, Houston, TX 77030

[2] Department of Biomathematics, M.D. Anderson Cancer Center, Houston

[3] Magnetic Resonance Department, Baylor University Medical Center, Dallas, TX 75246

来源：

MAGNETIC RESONANCE IMAGING | 1991年 / 9卷 / 03期

关键词：

MAGNETIC RESONANCE SPECTROSCOPY; BRAIN; STIMULATED ECHO SEQUENCE;

D O I：

10.1016/0730-725X(91)90415-I

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

In vivo localized proton magnetic resonance spectroscopy (MRS) studies of brain were performed on eighteen normal subjects using the stimulated echo (STE) sequence. The absolute concentrations and proton relaxation times of N-acetyl aspartate (NAA), total creatine (Cr) and choline (Cho) were estimated. The MRS data was quantitatively analyzed for repeatability and intersubject variability. Quantitative analysis indicates excellent spectral repeatability. Significant intersubject variations in [NAA] and [Cr] have been observed while the intersubject variability in [Cho] has been found to be fairly small. Significant intensity distortions have been observed for mixing times longer than 50 msec.

引用

页码：303 / 308

页数：6

共 25 条

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