MONOTHERAPY WITH LABETALOL FOR HYPERTENSIVE PATIENTS WITH NORMAL AND IMPAIRED RENAL-FUNCTION

被引：17

作者：

THOMPSON, FD ^{[1
]}

JOEKES, AM ^{[1
]}

HUSSEIN, MM ^{[1
]}

机构：

[1] INST UROL,LONDON,ENGLAND

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 1979年 / 8卷

关键词：

D O I：

10.1111/j.1365-2125.1979.tb04767.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

1 Labetalol was given to 41 hypertensive patients in a divided dosage of 150–2,400 mg daily for periods ranging from 1–64 months. 2 Monotherapy with labetalol was adequate in 12 out of 19 patients with essential hypertension and in 15 out of the 22 with renal hypertension. 3 Following a single dose of labetalol 200 mg orally a hypotensive response was seen between 1.5 and 2 hours. 4 In the doses used there was no exercise or postural hypotension. 5 No reduction in overall renal function attributable to labetalol was seen. 1979 The British Pharmacological Society

引用

页码：S129 / S133

页数：5