LITHIUM NEUROTOXICITY AT NORMAL THERAPEUTIC LEVELS

被引：54

作者：

BELL, AJ

COLE, A

ECCLESTON, D

FERRIER, IN

机构：

[1] University of Newcastle, Department of Psychiatry, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, Queen Victoria Road

来源：

BRITISH JOURNAL OF PSYCHIATRY | 1993年 / 162卷

关键词：

D O I：

10.1192/bjp.162.5.689

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Four cases of lithium-induced neurotoxicity are presented which, taken with evidence from previous reports, indicate that specific risk factors for lithium-induced neurotoxicity at normal serum levels are rapid dosage regimes, concomitant neuroleptic therapy, pre-existing EEG abnormalities, undetected cerebral pathology, organic impairment, and genetic susceptibility.

引用

页码：689 / 692

页数：4

共 10 条

[1]

DORUS E, 1975, ARCH GEN PSYCHIAT, V32, P1097

[2]

HAY G, 1982, LANCET, V2, P160

[3] INFLUENCE OF LITHIUM CARBONATE ON PATIENTS WITH TEMPORAL EPILEPSY [J].

JUS, A ;

VILLENEUVE, A ;

GAUTIER, J ;

PIRES, A ;

COTE, JM ;

JUS, K ;

VILLENEUVE, R ;

PERRON, D .

CANADIAN PSYCHIATRIC ASSOCIATION JOURNAL, 1973, 18 (01) :77-78

[4] REVERSIBLE LITHIUM NEUROTOXICITY AT NORMAL SERUM LEVEL MAY REFER TO INTRACRANIAL PATHOLOGY [J].

KEMPERMAN, CJF ;

GERDES, JH ;

DEROOIJ, J ;

VENCKEN, LM .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1989, 52 (05) :679-680

[5]

LEVINE SH, 1990, J CLIN PSYCHIAT, V51, P251

[6]

SANSONE MEG, 1985, CLIN NEUROPHARMACOL, V8, P242

[7]

SPRING GK, 1979, J CLIN PSYCHIAT, V40, P135

[8]

STRAYHORN JM, 1977, DIS NERV SYST, V38, P107

[9]

TYRER S, 1980, HDB LITHIUM THERAPY, P289

[10] A CASE OF LITHIUM NEUROTOXICITY WITH IRREVERSIBLE CEREBELLAR SYNDROME [J].

VERDOUX, H ;

BOURGEOIS, ML .

JOURNAL OF NERVOUS AND MENTAL DISEASE, 1990, 178 (12) :761-762

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