DISODIUM D-6-[ALPHA-(1,2,4-TRIAZINE-3,5-DIONE-6-CARBOXAMIDO)-4-HYDROXYPHENYLACETAMIDO]PENICILLANATE, BL-P1908

被引：3

作者：

BAKER, SR

HOLDREGE, CT

MCGREGOR, DN

机构：

[1] Research Division, Bristol Laboratories, Division of Bristol-Myers Company, Syracuse

来源：

JOURNAL OF ANTIBIOTICS | 1979年 / 32卷 / 05期

关键词：

D O I：

10.7164/antibiotics.32.468

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The synthesis of a new penicillin, disodium d-6-[α-(l, 2, 4-triazine-3,5-dione-6-carboxamido)-4-hydroxyphenylacetamido]penicillanate (BL-P1908), is described. The compound shows superior in vitro activity against Pseudomonas aeruginosa compared to carbenicillin and ticarcillin and produces higher intramuscular serum levels in mice than does carbenicillin. © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：468 / 471

页数：4

共 13 条

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[2]

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[3] COMPARATIVE ACTIVITY INVITRO OF TICARCILLIN, BL-P1654, AND CARBENICILLIN [J].

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[6] TICARCILLIN, CARBENICILLIN AND BL-P1908 INVITRO COMPARISON OF 3 ANTI-PSEUDOMONAL SEMISYNTHETIC PENICILLINS [J].

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[8]

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[9] ACTIVITY OF CARBENICILLIN AND TICARCILLIN AGAINST PSEUDOMONAS AERUGINOSA COMPARED BY PAIRED IN-VITRO TESTS [J].

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[10] COMPARATIVE INVITRO ACTIVITY AND CLINICAL PHARMACOLOGY OF TICARCILLIN AND CARBENICILLIN [J].

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GARVEY, GJ .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1975, 8 (04) :457-462

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