ANALYSIS OF THE GENE POLYMORPHISM OF ABO BLOOD-GROUP - SPECIFIC TRANSFERASES HELPS DIAGNOSIS OF ACQUIRED B-STATUS

被引：6

作者：

FISCHER, GF ^{[1
]}

FAE, I ^{[1
]}

DUB, E ^{[1
]}

PICKL, WF ^{[1
]}

机构：

[1] COUNCIL EUROPE,NATL TISSUE TYPING LAB,VIENNA,AUSTRIA

来源：

VOX SANGUINIS | 1992年 / 62卷 / 02期

关键词：

D O I：

10.1111/j.1423-0410.1992.tb01181.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Blood group typing of an aged patient suffering from ileus provided evidence for an acquired B. As a parameter independent of cell membrane molecules or secreted blood group substances, the nucleotide sequence polymorphism of A and B transferases was investigated. Restriction fragment length polymorphism of DNA chains amplified in a polymerase chain reaction from the coding region of the glycosyltransferase indicated that no gene for B transferase was present in the patient's genome. We conclude that the assessment of polymorphism of ABO blood group transferase can be used as a marker independent of blood group molecules for confirming a suspected acquired B.

引用

页码：113 / 116

页数：4

共 13 条

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