VISCOSITY AND STABILITY STUDIES OF LIQUID PARAFFIN EMULSIONS PREPARED BY HYDROXYPROPYL METHYLCELLULOSE

被引：2

作者：

FERDOUS, AJ

机构：

[1] Department of Pharmacy, University of Dhaka, Dhaka

来源：

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1993年 / 19卷 / 09期

关键词：

D O I：

10.3109/03639049309063002

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Liquid paraffin-water emulsions were prepared by three viscosity grades of hydroxypropyl methylcellulose (HPMC) polymer which showed pseudoplastic behavior. The viscosity of emulsions increased, but the mean droplet diameter of globules decreased on increasing the concentration of the polymer. On storage at 25-degrees-C. the viscosity of emulsions stabilized by low viscosity grade polymers increased. For higher viscosity polymer, the emulsion viscosity initially increased and then decreased slightly on aging. Lower viscosity grade HPMC polymers have higher emulsifying efficiency, whereas higher viscosity grade polymer emulsion is much more stable towards centrifugation.

引用

页码：1083 / 1088

页数：6

共 9 条

[1]

BIEHN GF, 1948, IND ENG CHEM, V40, P1449

[2]

BUSCALL R, 1975, PROG COLLOID POLY SC, V63, P15

[3] WATER-SOLUBLE CELLULOSE DERIVATIVES USES AS PRIMARY EMULSIFYING AGENTS .2. [J].