CLONIDINE-INDUCED CHANGES IN THE SPECTRAL DISTRIBUTION OF HEART-RATE-VARIABILITY CORRELATE WITH PERFORMANCE ON A TEST OF SUSTAINED ATTENTION

被引：12

作者：

MIDDLETON, HC ^{[1
]}

COULL, JT ^{[1
]}

SAHAKIAN, BJ ^{[1
]}

ROBBINS, TW ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,DEPT EXPTL PSYCHOL,CAMBRIDGE CB2 3EB,ENGLAND

来源：

JOURNAL OF PSYCHOPHARMACOLOGY | 1994年 / 8卷 / 01期

关键词：

CLONIDINE; HEART RATE; VARIABILITY; SPECTRAL ANALYSIS;

D O I：

10.1177/026988119400800101

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Conventional measures of cardiovascular activity correlate poorly with psychological variables and therefore provide imperfect physiological indices of arousal. We have investigated the effects of clonidine upon the spectral distribution of heart rate variability and upon performance on a test of sustained attention. Our findings suggest that activity of he central noradrenergic system influences the distribution of heart rate variability in the approximate to 0.1 Hz range. Furthermore, the finding of a strong correlation between the effects of clonidine upon each of these variables supports the use of spectral analysis of heart rate variability in the study of arousal.

引用

页码：1 / 7

页数：7

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