CAMPTOTHECIN, A SPECIFIC INHIBITOR OF TYPE-I DNA TOPOISOMERASE, INDUCES DNA BREAKAGE AT REPLICATION FORKS

[1] SELECTIVE INTERRUPTION OF HIGH MOLECULAR-WEIGHT RNA SYNTHESIS IN HELA-CELLS BY CAMPTOTHECIN [J]. NATURE-NEW BIOLOGY, 1972, 237 (74): : 144 - &

[2] CHARACTERIZATION OF A MAMMALIAN MUTANT WITH A CAMPTOTHECIN-RESISTANT DNA TOPOISOMERASE-I [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (16) : 5565 - 5569

[3] A HIGH-AFFINITY TOPOISOMERASE-1 BINDING SEQUENCE IS CLUSTERED AT DNAASE-1 HYPERSENSITIVE SITES IN TETRAHYMENA R-CHROMATIN [J]. CELL, 1985, 41 (02) : 541 - 551

[4] BOSMANN H B, 1970, Biochemical and Biophysical Research Communications, V41, P1412

[5] NEED FOR DNA TOPOISOMERASE ACTIVITY AS A SWIVEL FOR DNA-REPLICATION FOR TRANSCRIPTION OF RIBOSOMAL-RNA [J]. NATURE, 1987, 326 (6111) : 414 - 416

[6] CHEN GL, 1984, J BIOL CHEM, V259, P3560

[7] DNA TOPOISOMERASE-II MUTANT OF SACCHAROMYCES-CEREVISIAE - TOPOISOMERASE-II IS REQUIRED FOR SEGREGATION OF DAUGHTER MOLECULES AT THE TERMINATION OF DNA-REPLICATION [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (09): : 2616 - 2620

[8] INHIBITION OF DNA-SYNTHESIS BY APHIDICOLIN INDUCES SUPERCOILING IN SIMIAN-VIRUS 40 REPLICATIVE INTERMEDIATES [J]. EMBO JOURNAL, 1985, 4 (12) : 3241 - 3246

[9] LOCALIZATION OF SPECIFIC TOPOISOMERASE-I INTERACTIONS WITHIN THE TRANSCRIBED REGION OF ACTIVE HEAT-SHOCK GENES BY USING THE INHIBITOR CAMPTOTHECIN [J]. MOLECULAR AND CELLULAR BIOLOGY, 1987, 7 (01) : 141 - 148

[10] TOPOISOMERASE-I INTERACTS WITH TRANSCRIBED REGIONS IN DROSOPHILA CELLS [J]. CELL, 1986, 44 (03) : 401 - 407

[1] SELECTIVE INTERRUPTION OF HIGH MOLECULAR-WEIGHT RNA SYNTHESIS IN HELA-CELLS BY CAMPTOTHECIN [J]. NATURE-NEW BIOLOGY, 1972, 237 (74): : 144 - &

[2] CHARACTERIZATION OF A MAMMALIAN MUTANT WITH A CAMPTOTHECIN-RESISTANT DNA TOPOISOMERASE-I [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (16) : 5565 - 5569

[3] A HIGH-AFFINITY TOPOISOMERASE-1 BINDING SEQUENCE IS CLUSTERED AT DNAASE-1 HYPERSENSITIVE SITES IN TETRAHYMENA R-CHROMATIN [J]. CELL, 1985, 41 (02) : 541 - 551

[4] BOSMANN H B, 1970, Biochemical and Biophysical Research Communications, V41, P1412

[5] NEED FOR DNA TOPOISOMERASE ACTIVITY AS A SWIVEL FOR DNA-REPLICATION FOR TRANSCRIPTION OF RIBOSOMAL-RNA [J]. NATURE, 1987, 326 (6111) : 414 - 416

[6] CHEN GL, 1984, J BIOL CHEM, V259, P3560

[7] DNA TOPOISOMERASE-II MUTANT OF SACCHAROMYCES-CEREVISIAE - TOPOISOMERASE-II IS REQUIRED FOR SEGREGATION OF DAUGHTER MOLECULES AT THE TERMINATION OF DNA-REPLICATION [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (09): : 2616 - 2620

[8] INHIBITION OF DNA-SYNTHESIS BY APHIDICOLIN INDUCES SUPERCOILING IN SIMIAN-VIRUS 40 REPLICATIVE INTERMEDIATES [J]. EMBO JOURNAL, 1985, 4 (12) : 3241 - 3246

[9] LOCALIZATION OF SPECIFIC TOPOISOMERASE-I INTERACTIONS WITHIN THE TRANSCRIBED REGION OF ACTIVE HEAT-SHOCK GENES BY USING THE INHIBITOR CAMPTOTHECIN [J]. MOLECULAR AND CELLULAR BIOLOGY, 1987, 7 (01) : 141 - 148

[10] TOPOISOMERASE-I INTERACTS WITH TRANSCRIBED REGIONS IN DROSOPHILA CELLS [J]. CELL, 1986, 44 (03) : 401 - 407