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NEW ANTIBIOTICS FROM STRAINS OF TRICHODERMA-HARZIANUM

被引：76
作者：
ALMASSI, F
GHISALBERTI, EL
NARBEY, MJ
SIVASITHAMPARAM, K
机构：
[1] UNIV WESTERN AUSTRALIA,SCH AGR,DEPT ORGAN CHEM,NEDLANDS,WA 6009,AUSTRALIA
[2] UNIV WESTERN AUSTRALIA,SCH AGR,SOIL SCI & PLANT NUTR GRP,NEDLANDS,WA 6009,AUSTRALIA
来源：
JOURNAL OF NATURAL PRODUCTS | 1991年 / 54卷 / 02期
关键词：
D O I：
10.1021/np50074a008
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The metabolites produced in liquid cultures by two strains of Trichoderma harzianum, isolated from wheat roots, have been examined. Strain 71 produces three compounds with antibiotic activity towards the take-all fungus, Gaeumannomyces graminis var. tritici. Compounds 1 and 2 have been isolated previously from strains of Trichoderma koningii and T. harzianum. The structure of the third and major metabolite 3, an octaketide-derived acetal diol, has been deduced from detailed spectroscopic analysis of 3 and its derivatives. Strain 73 elaborates two new butenolide metabolites containing the 3,4-dialkylfuran-2(5H)-one nucleus. Both metabolites antagonize the growth of the take-all fungus.
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页码：396 / 402
页数：7
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