DETECTION OF HUMAN PAPILLOMAVIRUS DNA IN CERVICAL SMEARS BY THE POLYMERASE CHAIN-REACTION

被引：1

作者：

CHETSANGA, C

PETTERSSON, B

PETTERSSON, U

GYLLENSTEN, U

机构：

[1] UNIV UPPSALA, CTR BIOMED, DEPT MED GENET, BOX 589, S-75123 UPPSALA, SWEDEN

[2] UNIV HOSP UPPSALA, DEPT GYNECOL ONCOL, UPPSALA, SWEDEN

[3] UNIV UPPSALA, DEPT MED GENET, S-75105 UPPSALA, SWEDEN

[4] UNIV ZIMBABWE, DEPT BIOCHEM, HARARE, ZIMBABWE

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER | 1991年 / 1卷 / 05期

关键词：

CERVICAL SMEAR; CERVIX NEOPLASM; HUMAN PAPILLOMAVIRUS; POLYMERASE CHAIN REACTION;

D O I：

10.1111/j.1525-1438.1991.tb00042.x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A PCR-based method has been developed which allows human papillomavirus DNA to be detected in routinely obtained cervical smear specimens. The results showed that 76% of the smears that were collected from women who were carrying HPV-positive lesions by cervical swab analysis were positive by the PCR-based method. The results suggest that it is possible to carry out population-based retrospective studies of archival cervical smears.

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页码：209 / 213

页数：5

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