SUGAR CHAIN HETEROGENEITY OF BONE AND LIVER ALKALINE-PHOSPHATASE IN SERUM

被引：13

作者：

KUWANA, T

SUGITA, O

YAKATA, M

机构：

来源：

ENZYME | 1991年 / 45卷 / 1-2期

关键词：

SUGAR CHAINS; HETEROGENEITY; ALKALINE PHOSPHATASE ISOENZYME;

D O I：

10.1159/000468866

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Fractionation of bone and liver alkaline phosphatase (EC 3.1.3.1; ALP) in serum by serial lectin affinity chromatography has demonstrated differences in the sugar chain structure of bone and liver ALP in serum from that previously reported in the corresponding tissues, with a lower content of high mannose or hybrid-type sugar chains and a higher content of biantennary complex-type chains. Furthermore, the bone and liver ALPs were found to differ in the latter with the bone fraction showing a greater content of fucose residues.

引用

页码：63 / 66

页数：4

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