CHEMICAL-STABILITY OF INDOMETHACIN IN THE SOLID AMORPHOUS AND MOLTEN STATES

被引:22
作者
CARSTENSEN, JT
MORRIS, T
机构
[1] School of Pharmacy, University of Wisconsin, Madison, Wisconsin
[2] Eli Lilly and Company, Indianapolis, Indiana, 46285
关键词
D O I
10.1002/jps.2600820622
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
It is shown that the decomposition of an amorphous substance at temperatures close to the melting point of the stable, crystalline modification equals in order and activation parameters that of the molten substance.
引用
收藏
页码:657 / 659
页数:3
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