N6-(DELTA2-ISOPENTENYL)ADENOSINE - BIOSYNTHESIS IN VITRO BY AN ENZYME EXTRACT FROM YEAST AND RAT LIVER

被引：44

作者：

FITTLER, F

KLINE, LK

HALL, RH

机构：

[1] Department of Experimental Therapeutics, Roswell Park Memorial Institute, Buffalo

[2] Department of Biochemistry, State University of New York at Buffalo, Buffalo

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1968年 / 31卷 / 04期

关键词：

D O I：

10.1016/0006-291X(68)90516-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A cell-free extract from either rat liver or yeast catalyzes the incorporation of mevalonic acid or Δ3-isopentenyl pyrophosphate into preformed transfer-RNA to form N6-(Δ2-isopentenyl)adenosine. Treatment of the t-RNA with permanganate under mild conditions enhances its capacity to accept the isopentenyl side chain. © 1968.

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页码：571 / &

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