CYCLIC AMP-DEPENDENT AND AMP-INDEPENDENT PROTEIN-KINASES OF THE WATER MOLD, BLASTOCLADIELLA-EMERSONII

被引：12

作者：

JULIANI, MH

DACOSTAMAIA, JC

机构：

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 567卷 / 02期

基金：

巴西圣保罗研究基金会;

关键词：

(Blastocladiella emersonii); Cyclic AMP; Protein kinase;

D O I：

10.1016/0005-2744(79)90121-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Protein kinase (ATP:protein phosphotrasferase, EC 2.7.1.37) and cyclic adenosine 3′,5′-monophosphate binding activities have been identified in zoospore extracts of the water mold Blastocladiella emersonii. More than 75% of these activities is found in the soluble fraction. Soluble protein kinase activity is resolved in three peaks (I, II and III) by DEAE-cellulose chromatography. Peak I is casein dependent and insensitive to cyclic AMP. Peak II is histone dependent and cyclic AMP independent; this enzyme is inhibited by the heat-stable inhibitor from bovine muscle, Peak III utilizes histone as substrate and is activated by cyclic AMP. © 1979.

引用

页码：347 / 356

页数：10

共 20 条

[1] FACTORS AFFECTING ACTIVITY OF MUSCLE GLYCOGEN SYNTHETASE .3. REACTION WITH ADENOSINE TRIPHOSPHATE MG++ AND CYCLIC 3'5'-ADENOSINE MONOPHOSPHATE [J].