REDUCTION OF INDOLIN-2-ONES AND DESULFURIZATION OF INDOLINE-2-THIONES TO INDOLINE AND INDOLE-DERIVATIVES

被引：17

作者：

NISHIO, T

OKUDA, N

KASHIMA, C

机构：

[1] Department of Chemistry, University of Tsukuba, Tsukuba-Shi, Ibaraki

来源：

HELVETICA CHIMICA ACTA | 1990年 / 73卷 / 06期

关键词：

D O I：

10.1002/hlca.19900730616

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reduction of indolin‐2‐ones with lithium aluminium hydride (LAH) or diisobutylaluminum hydride (DIBAL) and desulfurization of indoline‐2‐thiones with Raney‐Ni were investigated. Treatment of indoline‐2‐ones 1 with LAH or DIBAL yield indoles 4 and/or indolines 3 in moderate‐to high yield depending on the substituents at N and C(3) of 1. Indoline‐2‐thiones 2 were desulfurized with Raney‐Ni to give indoles 4 and/or indolines 3. Copyright © 1990 Verlag GmbH & Co. KGaA, Weinheim

引用

页码：1719 / 1723

页数：5

共 12 条

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