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JUNCTIONAL MODULATION IN MOUSE EMBRYONAL CARCINOMA-CELLS BY FAB FRAGMENTS OF RABBIT ANTI-EMBRYONAL CARCINOMA CELL SERUM

被引：21
作者：
DUNIA, I
NICOLAS, JF
JAKOB, H
BENEDETTI, EL
JACOB, F
机构：
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1979年 / 76卷 / 07期
关键词：
D O I：
10.1073/pnas.76.7.3387
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Mouse embryonal carcinoma PCC4 cells are connected by extensive gap and tight junctions. When the cells are incubated in a medium containing Fab fragments against embryonal carcinoma F9 cells, they round up and a process of junctional removal is initiated. In particular, gap junctions are internalized and after 30 hr of incubation with the anti-F9 Fab fragments both tight and gap junctions are no longer present at the cell surface; however, the cells are still in contact by means of small attachment sites.
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页码：3387 / 3391
页数：5
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