CONVENIENT PREPARATION OF 5'-CHLORO-2',5'-DIDEOXYADENOSINE

被引：14

作者：

BEACHAM, LM

机构：

[1] Department of Experimental Therapy, Burroughs Wellcome Company, Research Triangle Park

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1979年 / 44卷 / 18期

关键词：

D O I：

10.1021/jo01332a002

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title compound was prepared by treating 2'-deoxyadenosine with 1.5 equiv of SOCl2 in hexamethylphosphoramide. An intermediate bis sulfite was isolated and characterized. © 1979, American Chemical Society. All rights reserved.

引用

页码：3100 / 3101

页数：2

共 7 条

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[2] IMPROVED SYNTHESES OF CHLORODEOXYNUCLEOSIDES
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[5] REACTION OF 1-(2,3-O-ISOPROPYLIDENE-BETA-D-RIBOFURANOSYL) URACIL WITH EXCESS THIONYL CHLORIDE - FORMATION OF BIS[1-(2,3-O-ISOPROPYLIDENE-BETA-D-RIBOFURANOSYL) URACIL] 5'-SULFITE
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[J]. CARBOHYDRATE RESEARCH, 1973, 27 (02) : 455 - 459
[6] HALO SUGAR NUCLEOSIDES .3. REACTIONS FOR CHLORINATION AND BROMINATION OF NUCLEOSIDE HYDROXYL GROUPS
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[7] REINVESTIGATION OF SYNTHESIS OF 2'-DEOXYADENOSYLHOMOCYSTEINE
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