DELAYED-EFFECTS OF SUBARACHNOID HEMORRHAGE ON CEREBRAL METABOLISM AND THE CEREBROVASCULAR RESPONSE TO HYPERCAPNIA IN THE PRIMATE

被引:17
作者
BOISVERT, DPJ
PICKARD, JD
GRAHAM, DI
FITCH, W
机构
[1] UNIV GLASGOW,DEPT NEUROL,GLASGOW G12 8QQ,SCOTLAND
[2] UNIV GLASGOW,DEPT NEUROPATHOL,GLASGOW G12 8QQ,SCOTLAND
[3] UNIV GLASGOW,DEPT ANESTHESIA,GLASGOW G12 8QQ,SCOTLAND
[4] WELLCOME SURG RES INST,GLASGOW,SCOTLAND
关键词
D O I
10.1136/jnnp.42.10.892
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A technique is described for the production of subarachnoid haemorrhage in baboons and their subsequent recovery for chronic study of cerebrovascular reactivity. The baboons make complete neurological recoveries but the response of their cerebral circulation to hypercapnia is impaired one week later. Baseline values of cerebral blood flow and of cerebral oxygen consumption are unaffected at this time. There is no evidence of hypoxic brain damage.
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页码:892 / 898
页数:7
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