NAPHTHALENE-CATALYZED REDUCTIVE DESULFONYLATION WITH LITHIUM - ALKYLLITHIUMS FROM ALKYL PHENYL SULFONES

被引：27

作者：

GUIJARRO, D ^{[1
]}

YUS, M ^{[1
]}

机构：

[1] UNIV ALICANTE,FAC CIENCIAS,DEPT QUIM ORGAN,E-03080 ALICANTE,SPAIN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 18期

关键词：

D O I：

10.1016/S0040-4039(00)76673-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of alkyl aryl sulfones 1 with an excess of lithium powder and a catalytic amount of naphthalene (8 mol %) in the presence of a carbonyl compound [(PrCHO)-C-i, PhCHO, Et(2)CO, (CH2)(5)CO] or trimethylchlorosilane (Barbier-type conditions) in THF at temperatures ranging between -78 and 20 degrees C leads, after hydrolysis with water, to the expected coupling products, arising from the corresponding alkyllithium in situ generated, in 30-61% yields.

引用

页码：2965 / 2968

页数：4

共 44 条

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