AN INVESTIGATION INTO NATURE OF INTRACELLULAR INCLUSIONS FORMED BY MUMPS VIRUS AS DETERMINED BY COMBINED USE OF IMMUNOFLUORESCENCE AND METHYLGREEN-PYRONIN STAIN

被引:5
作者
NASIBOV, MN
SMORODIN.AA
机构
[1] State Research Institute of Influenza, Leningrad
[2] Research Institute of Virology, Microbiology and Hygiene
来源
ARCHIV FUR DIE GESAMTE VIRUSFORSCHUNG | 1968年 / 24卷 / 04期
关键词
D O I
10.1007/BF01243073
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Tissue cultures inoculated with mumps virus have been shown by cytological and fluorescent techniques to contain inclusion bodies which give an indication of the amount of infectious virus in the inoculum and of the sensitivity of the tissue culture to infection; inclusion body formation is inversely proportional to the susceptibility of the tissue culture to infection with the virus. It was found that inclusions developed at all times in the reproductive cycle, even when infectious virus was undetectable. This phenomenon was demonstrated in serial preparations by the simultaneous use of histochemical and fluorescent methods for the detection of inclusions. © 1968 Springer-Verlag.
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页码:319 / &
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