ENANTIODIVERGENT TOTAL SYNTHESIS OF NATURALLY-OCCURRING TRANS-2-BUTYL-5-PENTYLPYRROLIDINE

被引：28

作者：

MACHINAGA, N ^{[1
]}

KIBAYASHI, C ^{[1
]}

机构：

[1] TOKYO COLL PHARM,HORINOUCHI,HACHIOJI,TOKYO 19203,JAPAN

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 25期

关键词：

D O I：

10.1016/S0040-4039(00)94464-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The enantiodivergent total synthesis of (+)-(2S,5S)- and (-)-(2R,SR)-trans-2-butyl-5-pentylpyrrolidines was effected from the C2 symmetric (S,S)- and (R,R)-diepoxides, respectively, both prepared from Dmannitol, by a sequence involving stereo-defined ring construction of the unsymmetrical trans-2,5-dialkylpyrrolidine via the cyclic sulfate as a key step. © 1990.

引用

页码：3637 / 3640

页数：4

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