ZINC AND INSULIN SENSITIVITY

被引：62

作者：

FAURE, P ^{[1
]}

ROUSSEL, A ^{[1
]}

COUDRAY, C ^{[1
]}

RICHARD, MJ ^{[1
]}

HALIMI, S ^{[1
]}

FAVIER, A ^{[1
]}

机构：

[1] UNIV JOSEPH FOURIER,RECH METAB LAB,F-38700 LA TRONCHE,FRANCE

来源：

BIOLOGICAL TRACE ELEMENT RESEARCH | 1992年 / 32卷

关键词：

DIABETES-MELLITUS; ZINC DEFICIENCY; INSULIN-RESISTANCE; ANTIOXIDANT; INSULIN RECEPTOR; GLUCOSE TRANSPORTER;

D O I：

10.1007/BF02784615

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Many studies have shown that zinc deficiency could decrease the response to insulin. In genetically diabetic animals, a low zinc status has been observed contrary to induced diabetic animals. The zinc status of human patients depends on the type of diabetes and the age. Zinc supplementation seems to have beneficial effects on glucose homeostatis. However, the mechanism of insulin resistance secondary to zinc depletion is yet unclear. More studies are therefore necessary to document better zinc metabolism in diabetes mellitus, and the antioxidant activity of zinc on the insulin receptor and the glucose transporter.

引用

页码：305 / 310

页数：6

共 21 条

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