PRODUCTION OF A LIPOPEPTIDE ANTIBIOTIC SURFACTIN WITH RECOMBINANT BACILLUS-SUBTILIS

被引:27
作者
OHNO, A [1 ]
ANO, T [1 ]
SHODA, M [1 ]
机构
[1] TOKYO INST TECHNOL,RESOURCES UTILIZAT RES LAB,4259 NAGATSUTA,MIDORI KU,YOKOHAMA,KANAGAWA 227,JAPAN
关键词
D O I
10.1007/BF01027022
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Production of a lipopeptide antibiotic surfactin was carried out using a recombinant Bacillus subtilis. Surfactin yield of the recombinant strain was about one and half times as much as that of Bacillus subtilis RB14, the strain in which the surfactin gene was originated. This system is especially noteworthy because a recombinant strain surpassed the original strain in the production of a bacterial antibiotic as a secondary metabolite of the bacterium.
引用
收藏
页码:1165 / 1168
页数:4
相关论文
共 8 条