CYTOGENETIC AND FISH STUDIES OF ABNORMAL-X CHROMOSOMES IN A PATIENT WITH ANLL

被引：9

作者：

CHEN, Z

BERGER, CS

MORGAN, R

ROTH, D

STONE, JF

SANDBERG, AA

机构：

[1] SBRI & GENETRIX INC,CTR CANC,6401 E THOMAS RD,SCOTTSDALE,AZ 85251

[2] NEW ENGLAND MED CTR,BOSTON,MA 02111

来源：

CANCER GENETICS AND CYTOGENETICS | 1992年 / 62卷 / 02期

关键词：

D O I：

10.1016/0165-4608(92)90250-C

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report a case of idic[X][q13],r[X][p22q13], and del[X][:p11-->cen-->q11:] in a 71-year-old female patient with de novo acute nonlymphocytic leukemia [ANLL], FAB-M4. The abnormal X chromosomes of this patient were identified cytogenetically by G-banding technique and were further confirmed by fluorescence in situ hybridization (FISH) using an alpha-satellite probe to chromosome X centromere. The features of this are compared with other cases reported in the literature.

引用

页码：130 / 133

页数：4

共 6 条

[1] 26 PATIENTS WITH HEMATOLOGIC DISORDERS AND X-CHROMOSOME ABNORMALITIES FREQUENT IDIC(X)(Q13) CHROMOSOMES AND XQ13 ANOMALIES ASSOCIATED WITH PATHOLOGIC RINGED SIDEROBLASTS [J].