AN EFFICIENT SYNTHESIS OF POLYOXAMIC ACID UTILIZING THE ARYL GROUP AS THE CARBOXYL SYNTHON - A NEW APPROACH TO POLYHYDROXYAMINO ACIDS

被引：49

作者：

MATSUURA, F ^{[1
]}

HAMADA, Y ^{[1
]}

SHIOIRI, T ^{[1
]}

机构：

[1] NAGOYA CITY UNIV,FAC PHARMACEUT SCI,MIZUHO KU,NAGOYA,AICHI 467,JAPAN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(00)75803-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Polyoxamic acid (1), an amino acid moiety of antifungal antibiotics polyoxins, has been efficiently synthesized from Boc-(R)4-hydroxyphenylglycine (3) utilizing its aryl group as the carboxyl synthon.

引用

页码：733 / 736

页数：4

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