SURGICAL-MANAGEMENT OF THE HEAD AND NECK-CANCER PATIENT FOLLOWING CONCOMITANT MULTIMODALITY THERAPY

被引:26
作者
PANJE, WR
NAMON, AJ
VOKES, E
HARAF, DJ
WEICHSELBAUM, RR
机构
[1] UNIV CHICAGO, DEPT MED, HEMATOL ONCOL SECT, CHICAGO, IL 60637 USA
[2] UNIV CHICAGO, DEPT RADIAT THERAPY, CHICAGO, IL 60637 USA
关键词
D O I
10.1288/00005537-199501000-00021
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The simultaneous use of chemotherapy and radiotherapy (concomitant therapy) has exceptional promise in the treatment of head and neck cancer. In this limited review, seven head and neck cancer patients who underwent prior concomitant therapy and subsequent surgery developed wound-healing complications that were delayed (22-day average) in onset. Paranasal sinus and base of skull operations had less significant wound morbidity than those cases requiring simultaneous transgression of the neck and upper aerodigestive tract. The use of arterialized flaps did not in itself prevent wound breakdown. The formation of controlled fistulae, delay of reconstruction, and avoidance of simultaneous neck and upper aerodigestive tract entry are important considerations in avoiding wound-healing complications after concomitant therapy. In this select group of patients, surgery should be approached with extreme caution and conservatism.
引用
收藏
页码:97 / 101
页数:5
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