LYSOSOMAL LOCALIZATION OF SPHINGOLIPID HYDROLASES

被引：109

作者：

WEINREB, NJ

BRADY, RO

TAPPEL, AL

机构：

[1] Laboratory of Neurochemistry, National Institute of Neurological Diseases and Blindness, National Institutes of Health, Bethesda, MD

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1968年 / 159卷 / 01期

关键词：

D O I：

10.1016/0005-2744(68)90251-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The distribution of three sphingolipid hydrolases was studied in subcellular fractions of rat liver and kidney tissue. Lysosomes contained the highest specific activity with regard to glucocerebrosidase, galactocerbrosidase, and sphingomyelinase. Considerable sphingomyelinase activity is also found in mitochondria and microsomes which is probably not attributable to lysosomal contamination. © 1968.

引用

页码：141 / +

页数：1

共 32 条

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