ETHYL SUBSTITUTION AT THE 7-POSITION EXTENDS THE HALF-LIFE OF 10-HYDROXYCAMPTOTHECIN IN THE PRESENCE OF HUMAN SERUM-ALBUMIN

被引：95

作者：

BURKE, TG ^{[1
]}

MI, Z ^{[1
]}

机构：

[1] OHIO STATE UNIV,CTR COMPREHENS CANC,COLUMBUS,OH 43210

来源：

关键词：

D O I：

10.1021/jm00069a020

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：2580 / 2582

页数：3

共 13 条

[1] Burke SR, 1980, COMPOSITION FUNCTION
[2] LIPID BILAYER PARTITIONING AND STABILITY OF CAMPTOTHECIN DRUGS
BURKE, TG
MISHRA, AK
WANI, MC
WALL, ME
[J]. BIOCHEMISTRY, 1993, 32 (20) : 5352 - 5364
[3] LIPOSOMAL STABILIZATION OF CAMPTOTHECINS LACTONE RING
BURKE, TG
STAUBUS, AE
MISHRA, AK
MALAK, H
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (21) : 8318 - 8319
[4] PREFERENTIAL BINDING OF THE CARBOXYLATE FORM OF CAMPTOTHECIN BY HUMAN SERUM-ALBUMIN
BURKE, TG
MI, ZH
[J]. ANALYTICAL BIOCHEMISTRY, 1993, 212 (01) : 285 - 287
[5] DNA TOPOISOMERASE-I TARGETED CHEMOTHERAPY OF HUMAN-COLON CANCER IN XENOGRAFTS
GIOVANELLA, BC
STEHLIN, JS
WALL, ME
WANI, MC
NICHOLAS, AW
LIU, LF
SILBER, R
POTMESIL, M
[J]. SCIENCE, 1989, 246 (4933) : 1046 - 1048
[6] GIOVANELLA BC, 1991, CANCER RES, V51, P3052
[7] MODIFICATION OF THE HYDROXY LACTONE RING OF CAMPTOTHECIN - INHIBITION OF MAMMALIAN TOPOISOMERASE-I AND BIOLOGICAL-ACTIVITY
HERTZBERG, RP
CARANFA, MJ
HOLDEN, KG
JAKAS, DR
GALLAGHER, G
MATTERN, MR
MONG, SM
BARTUS, JO
JOHNSON, RK
KINGSBURY, WD
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (03) : 715 - 720
[8] KANEDA N, 1990, CANCER RES, V50, P1715
[9] Lakowicz J. R., 2010, PRINCIPLES FLUORESCE
[10] THE CURRENT STATUS OF CAMPTOTHECIN ANALOGS AS ANTITUMOR AGENTS
SLICHENMYER, WJ
ROWINSKY, EK
DONEHOWER, RC
KAUFMANN, SH
[J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1993, 85 (04): : 271 - 291