ANALGESIC ACTIVITY OF NOVEL SPIRO HETEROCYCLES - 2-AMINO-7-OXA-3-THIA-1-AZASPIRO[5.5]UNDEC-1-ENES AND RELATED COMPOUNDS

被引：7

作者：

COHEN, N ^{[1
]}

BANNER, BL ^{[1
]}

LOPRESTI, RJ ^{[1
]}

BARUTH, HW ^{[1
]}

机构：

[1] HOFFMANN LA ROCHE INC,DEPT PHARMACOL,NUTLEY,NJ 07110

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1978年 / 21卷 / 09期

关键词：

D O I：

10.1021/jm00207a011

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：895 / 900

页数：6

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[4] SYNTHESIS OF 2-AMINO-5,6-DIHYDRO-4H-1,3-THIAZINES AND RELATED COMPOUNDS BY ACID-CATALYZED CYCLIZATION OF ALLYLIC ISOTHIURONIUM SALTS [J].

COHEN, N ;

BANNER, BL .

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[5] SYNTHESIS OF NOVEL SPIRO HETEROCYCLES - 2-AMINO-7-OXA-3-THIA-1-AZASPIRO[5.5]UNDEC-1-ENES [J].

COHEN, N ;

BANNER, BL ;

BLOUNT, JF ;

WEBER, G ;

TSAI, M ;

SAUCY, G .

JOURNAL OF ORGANIC CHEMISTRY, 1974, 39 (13) :1824-1833

[6]

DEWEY WL, 1975, METHODS NARCOTIC RES, P101

[7]

FIESER LF, 1967, REAGENTS ORGANIC SYN, V1, P1210

[8]

HENDERSHOT LC, 1959, J PHARMACOL EXP THER, V125, P237

[9]

KALMAN A, 1977, TETRAHEDRON LETT, P4241

[10]

KAPPELER H, 1954, HELV CHIM ACTA, V37, P957

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