ULTRASTRUCTURE OF GIANT-CELL LESIONS - A PERIPHERAL GIANT-CELL REPARATIVE GRANULOMA

被引:14
作者
ADKINS, KF
MARTINEZ, MG
HARTLEY, MW
机构
[1] Department of Pathology, University of Alabama Medical Center Birmingham, AL
来源
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS | 1969年 / 28卷 / 05期
关键词
D O I
10.1016/0030-4220(69)90420-4
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
The morphologic features of the cells in a peripheral giant-cell granuloma of the mandible were examined with the electron microscope. The principal structural features of the multinucleated giant cells included extremely irregular nuclear and cytoplasmic membranes, very large and prominent nucleoli, and huge concentrations of mitochondria and vesicles within the cytoplasm. Dense bodies similar to those which are considered to represent lysosomes in other cells were seldom seen in the giant cells but were present in several mononuclear stromal cells. There was no evidence of phagocytosis of fragmented erythrocytes, granules of pigment, or foreign material by the giant cells, but mononuclear macrophages were active in this respect. The giant cells are not simply larger versions of the stromal cells which are thought to produce them. They are highly differentiated cells with an organelle content distinctly different from that of any of the stromal cells. © 1969 The C. V. Mosby Company.
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页码:713 / &
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