L-THYROXINE TREATMENT OF DIFFUSE NON-TOXIC GOITER EVALUATED BY ULTRASONIC DETERMINATION OF THYROID VOLUME

被引：54

作者：

HANSEN, JM ^{[1
]}

KAMPMANN, J ^{[1
]}

MADSEN, SN ^{[1
]}

SKOVSTED, L ^{[1
]}

SOLGAARD, S ^{[1
]}

GRYTTER, C ^{[1
]}

GRONTVEDT, T ^{[1
]}

RASMUSSEN, SN ^{[1
]}

机构：

[1] HERLEV HOSP,ULTRASON LAB,DK-2730 HERLEV,DENMARK

来源：

CLINICAL ENDOCRINOLOGY | 1979年 / 10卷 / 01期

关键词：

D O I：

10.1111/j.1365-2265.1979.tb03027.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The effect of a daily dose of 150 μg 1‐thyroxine for one year was studied in forty‐five patients with diffuse non‐toxic goitre. Thyroid volume was evaluated by ultrasonic scanning. A decrease in the median value of the thyroid volume of about 20% was found after 3 months of therapy and no further change in the median value was observed in the following 9 months of treatment. About 50% of the patients showed a response to therapy and about 30% obtained normal size of the thyroid gland. Median value of the thyroid volume returned to pretreatment value 3 months after thyroxine therapy was stopped. A considerable increase in serum T4 and free T4 index was noted after 3 months of therapy and these elevated values persisted unaltered during the following 9 months of treatment. Serum T3 was studied before and after 3 months of thyroxine therapy in eleven of the patients. A small and insignificant increase in serum T3 and free T3 index was observed. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：1 / 6

页数：6

共 18 条

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