YEAST MITOCHONDRIAL ATP-DEPENDENT PROTEASE - PURIFICATION AND COMPARISON WITH THE HOMOLOGOUS RAT ENZYME AND THE BACTERIAL ATP-DEPENDENT PROTEASE LA

被引：34

作者：

KUTEJOVA, E ^{[1
]}

DURCOVA, G ^{[1
]}

SUROVKOVA, E ^{[1
]}

KUZELA, S ^{[1
]}

机构：

[1] SLOVAK ACAD SCI, INST MOLEC BIOL, DUBRAVSKA 21, CS-84251 BRATISLAVA, CZECHOSLOVAKIA

来源：

FEBS LETTERS | 1993年 / 329卷 / 1-2期

关键词：

YEAST MITOCHONDRIA; ATP-DEPENDENT PROTEASE; INTRAMITOCHONDRIAL PROTEOLYSIS; PROTEASE LA; SACCHAROMYCES-CEREVISIAE;

D O I：

10.1016/0014-5793(93)80190-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Homogenous ATP-dependent protease has been isolated for the first time from mitochondria of the yeast Saccharomyces cerevisiae. The enzyme molecule consists of six 120 kDa subunits. It is a serine protease with an absolute ATP requirement for its activity. Basic enzymatic characteristics of the yeast protease are similar to those of the corresponding rat mitochondrial enzyme and of the E. coli protease La. The yeast enzyme immunochemically cross-reacts with the bacterial protease La.

引用

页码：47 / 50

页数：4

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