SYNTHESIS OF VARIOUS MODEL COMPOUNDS FOR THE CONJUGATED HETEROCYCLIC RING-SYSTEM OF ANTIBIOTIC ROSEOPHILIN

被引:35
作者
NAKATANI, S [1 ]
KIRIHARA, M [1 ]
YAMADA, K [1 ]
TERASHIMA, S [1 ]
机构
[1] SAGAMI CHEM RES CTR, SAGAMIHARA, KANAGAWA 229, JAPAN
关键词
D O I
10.1016/0040-4039(95)01822-Y
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The title synthesis was accomplished starting with 3-chloro-2-formylpyrrole. The synthetic scheme featured one-pot preparation of the 4-methoxy-2-(pyrrol-2-yl)furan from the 2-acetoacetyl-pyrrole and coupling reactions of the C-5-position of the 4-methoxy-2-(pyrrol-2-yl)furan with various types of aldehydes and ketones as key steps.
引用
收藏
页码:8461 / 8464
页数:4
相关论文
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