EPA IN THE PREVENTION OF RESTENOSIS POST PTCA

被引：9

作者：

BOWLES, MH ^{[1
]}

KLONIS, D ^{[1
]}

PLAVAC, TG ^{[1
]}

GONZALES, B ^{[1
]}

FRANCISCO, DA ^{[1
]}

ROBERTS, RW ^{[1
]}

BOXBERGER, GR ^{[1
]}

POLINER, LR ^{[1
]}

GALICHIA, JP ^{[1
]}

机构：

[1] WICHITA INST CLIN RES,WICHITA,KS

来源：

ANGIOLOGY | 1991年 / 42卷 / 03期

关键词：

D O I：

10.1177/000331979104200302

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

The effect of fish oil on restenosis was evaluated in patients undergoing coronary balloon angioplasty. In addition to routine pharmacotherapy, subjects were given 2.8 g of eicosapentanoic acid (EPA) daily. Treatment was started within twenty-four hours after successful percutaneous transluminal coronary angioplasty (PTCA). After six months of therapy, participants were subjected to coronary arteriography, exercise scintigraphy, exercise electrocardiography, or clinical evaluation. Follow-up evaluation involved 97 coronary lesions in 85 patients. Partial or significant restenosis occurred in 36.5% of patients and 33% of vessels. The presence of severe stenosis before PTCA, dissection, thrombus, multilesion PTCA, and template bleeding time values were not correlated with restenosis. Dilation of the left anterior descending (LAD) and a residual stenosis greater-than-or-equal-to 35% were associated with restenosis. Approximately 20% of the patients related difficulty in taking the fish oil. Furthermore, these results show no advantage over expected restenosis rates.

引用

页码：187 / 194

页数：8

共 33 条

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