TC-LABELED PANCAKE FOR STUDIES OF GASTRIC-EMPTYING OF SOLIDS

被引：12

作者：

HERMANSSON, G

SIVERTSSON, R

机构：

[1] Department of Clinical Physiology, Östra Hospital, University of Gothenburg, Gothernburg

来源：

NUCLEAR MEDICINE COMMUNICATIONS | 1991年 / 12卷 / 11期

关键词：

D O I：

10.1097/00006231-199111000-00007

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

To achieve a stable isotope marker of solid food, different variants of isotope-labelled Swedish pancake were tested. The marker stability was investigated by a new method assumed to test both the affinity of the isotope complex to the test meal and the mechanical stability. The test procedure included use of a gamma camera and human gastric juice. Pancakes labelled with either pertechnetate, (TcmO4)-TC-99 (Tc-pert), or Tc-99(m)-macroalbumin aggregates (Tc-MAA) were compared. The results showed a significant difference (P < 0.01), with 91.4 +/- 2.1% (mean +/- 1 S.D.) of activity remaining in the Tc-MAA pancake (n = 5) and only 81.1 +/- 5.8% in the Tc-pert pancake (n = 6) after 3 h. Pancakes labelled with Tc-MAA were also compared with chicken liver labelled in vivo with Tc-99(m)-sulphur colloid (Tc-SC). The results revealed significantly better marker stability (P < 0.05) of pancakes compared to chicken liver, with 83.0 +/- 9.1% remaining in the Tc-MAA pancake (n = 8) and 74.9 +/- 6.7% in the Tc-SC chicken liver (n = 8) after 180 min.

引用

页码：973 / 981

页数：9

共 22 条

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