CONTROL OF THE AQUEOUS ALDOL ADDITION UNDER CLAISEN-SCHMIDT CONDITIONS

被引：15

作者：

BUONORA, PT

ROSAUER, KG

DAI, LJ

机构：

[1] Department of Chemistry, Lamar University - Beaumont, Beaumont, TX 77710-0022

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 23期

关键词：

D O I：

10.1016/0040-4039(95)00700-M

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The influence of the addition of Lewis acid (zinc nitrate-hexahydrate) and Lewis base (N,N-dimethylaminoethanol) on the aqueous Claisen-Schmidt reaction was investigated The results demonstrate the preferential activation of the aldol addition reaction by the zinc ion under either specific or general base conditions. A protocol has been developed which selectively produces aldol addition products under aqueous conditions.

引用

页码：4009 / 4012

页数：4

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