EXISTENCE OF DNA SEQUENCES HOMOLOGOUS TO ADENOVIRUS 5-DNA IN THE GENOME OF NORMAL RAT-CELLS

被引:18
作者
FROLOVA, EI
GEORGIEV, GP
机构
[1] Institute of Molecular Biology, USSR Academy of Sciences, Moscow B-334
关键词
D O I
10.1093/nar/7.6.1419
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Three discrete bands specifically hybridizing to adeno- virus 5 MA were found in the rat liver DNA restricted by Bam HI endonuclease and fractionated electrophoretically. The hybridization with different regions of the viral genome takes place. Similar bands are present in the DNA from different lines of adenovirus 5 transformed cells, but in these cases high molecular weight DNA fragments containing the integrated viral genomes can also be found. © 1979 Information Retrieval Limited.
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页码:1419 / 1428
页数:10
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