FORENSIC ANALYSIS OF TRIAZOLAM IN HUMAN TISSUES USING CAPILLARY GAS-CHROMATOGRAPHY

被引：12

作者：

KUDO, K ^{[1
]}

NAGATA, T ^{[1
]}

IMAMURA, T ^{[1
]}

KAGE, S ^{[1
]}

HIDA, Y ^{[1
]}

机构：

[1] KYUSHU UNIV,FAC MED,DEPT FORENS MED,3-1-1 MAIDASHI,HIGASHI KU,FUKUOKA 812,JAPAN

来源：

INTERNATIONAL JOURNAL OF LEGAL MEDICINE | 1991年 / 104卷 / 02期

关键词：

TRIAZOLAM; ESTAZOLAM; CAPILLARY GC/NPD; HUMAN TISSUE; FORENSIC TOXICOLOGY;

D O I：

10.1007/BF01626033

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

A reliable and sensitive method has been developed to assess the concentrations of the hypnotic drug triazolam in human tissues, including putrefied tissues. The method involves a 3-step solvent extraction, clean-up on a silica gel column and gas chromatography using a nitrogen phosphorus detector and a capillary column. Estazolam was used as an internal standard. The calibration curve was linear over the concentration range 1 ng/g-1 mu-g/g and the lower limit of detection was 0.5 ng/g. A forensic study was performed on the toxicological effects of triazolam using putrefied tissues.

引用

页码：67 / 69

页数：3

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