EFFECTS OF ASPIRIN AND DIMENHYDRINATE (DRAMAMINE) ON VISUAL PROCESSES

1. The effect of three doses of either aspirin (1280 mg each) or dimenhydrinate (Dramamine) (100 mg each) in an 8 h period on visual processes was investigated double‐blind on sixteen volunteer subjects. 2. Tests included night‐vision, colour‐discrimination, stereoacuity and stereopsis, reaction‐time, pupil size, eye‐movements, visual evoked cortical potentials, electroencephalographs, a dial‐reading task, and a test of texture discrimination. 3. Both drugs affected colour discrimination, and dimenhydrinate degraded night‐vision, reaction‐ time, and stereopsis. 4. The effect of aspirin was minor, but the impairments produced by dimenhydrinate appear to be of practical importance. 1979 The British Pharmacological Society