NASOPHARYNGEAL COLONIZATION BY NONTYPABLE HAEMOPHILUS-INFLUENZAE IN CHILDREN - THE EFFECT OF SERUM BACTERICIDAL ANTIBODY

被引：12

作者：

BERNSTEIN, JM

FADEN, HS

OGRA, PL

机构：

[1] SUNY BUFFALO, DEPT PEDIAT, BUFFALO, NY 14214 USA

[2] SUNY BUFFALO, DEPT MICROBIOL, BUFFALO, NY 14214 USA

[3] CHILDRENS HOSP, BUFFALO, NY 14222 USA

来源：

OTOLARYNGOLOGY-HEAD AND NECK SURGERY | 1991年 / 105卷 / 03期

关键词：

D O I：

10.1177/019459989110500309

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

The effect of serum bactericidal antibody on colonization with NTHI was studied in 26 children. Serum bactericidal antibody did not prevent colonization with NTHI in the nasopharynx. Antibody was detected in 53% before, 91% during, and 100% after documented colonization. The log titer of antibody was significantly higher during (1.18 +/- 0.56), p < 0.002; and after (1.31 +/- 0.29), p > 0.001 compared to before colonization (0.49 +/- 0.51). The roles of secretory IgA and normal nasopharyngeal flora in inhibiting pathogenic bacteria are discussed.

引用

页码：406 / 410

页数：5

共 22 条

[1]

BERNSTEIN JM, 1990, J RESPIR DIS, V11, P402

[2] RESTRICTION FRAGMENT MAPPING OF BRANHAMELLA-CATARRHALIS - A NEW TOOL FOR STUDYING THE EPIDEMIOLOGY OF THIS MIDDLE-EAR PATHOGEN [J].